Skill UI

This guide details advanced methods for merging multiple specialized LLMs (e.g., combining math, coding, and chat capabilities) without the need for expensive retraining. Learn various techniques such as Linear Merging, SLERP, Task Arithmetic, TIES-Merging, and DARE. Use mergekit to create high-performing, specialized model variants quickly, significantly improving performance and reducing computational costs.

This skill provides comprehensive guidance on training Mixture of Experts (MoE) models, including architectures like Mixtral and DeepSeek-V3. It details techniques for achieving large-scale model capacity with significantly reduced computational costs (e.g., 5x reduction vs. dense models). Topics covered include top-k routing, load balancing, expert parallelism, and integration with frameworks like DeepSpeed and HuggingFace for efficient, resource-constrained training.

A comprehensive guide to leveraging Stable Diffusion models via the HuggingFace Diffusers library. This skill facilitates state-of-the-art image creation, including Text-to-Image generation from prompts, Image-to-Image translation, inpainting, outpainting, and advanced workflow building. Supports various models like SDXL and SD 3.0, ideal for professional creative and computational vision tasks.

Denario orchestrates a multi-agent AI to automate research workflows, covering idea generation, methodology development, computational experiments, and LaTeX publication output.

The ESM skill provides comprehensive tools for computational biology, leveraging ESM3 and ESM-C models. It enables sophisticated protein sequence generation, structure prediction (sequence to 3D structure), inverse folding (structure to sequence design), and generating function-conditioned proteins. Use it for de novo protein design, feature embedding, and advanced structural analysis in bioinformatics workflows.

Tamarind Bio is a cloud platform providing managed GPU access to hundreds of open-source computational biology tools. It facilitates complex tasks such as protein structure prediction (AlphaFold), de novo protein design, antibody engineering, protein-ligand docking, and molecular dynamics simulations. Users submit jobs via a unified API and receive predicted structures and biophysical scores without needing local high-performance computing resources.