Skill UI

This advanced toolkit provides a comprehensive framework for in-depth financial analysis. It covers key functions including financial ratio analysis, Discounted Cash Flow (DCF) valuation, budget variance analysis, and rolling forecast construction. It is essential for strategic decision-making, investment analysis, and management reporting across various industries.

Enables regression modeling via the regression-analysis-tool plugin by analyzing datasets, choosing linear or polynomial fits, validating models, and reporting metrics so users can predict outcomes or explore variable relationships.

Query NCBI ClinVar for variant clinical significance, mixing gene/condition searches, API/FTP downloads, and VCF annotations to support genomic medicine interpretation workflows.

Query Ensembl’s RESTful API to access gene annotations, sequences, variants, orthologs, and assembly mappings across 250+ species, enabling integration into genomic research pipelines.

Query the NHGRI-EBI GWAS Catalog for SNP-trait associations, fetch study metadata, variant and trait details, and download summary statistics via the web or REST APIs to support genetic epidemiology and polygenic risk modeling.

Pysam offers Python bindings to htslib for reading and writing SAM/BAM/CRAM alignments, VCF/BCF variants, and FASTA/FASTQ sequences, enabling coverage stats, pileup analysis, variant queries, and seamless integration into NGS pipelines.

Seaborn is a powerful Python library for creating publication-quality statistical graphics. It is designed for dataset-oriented plotting, making it ideal for exploratory data analysis, multivariate analysis, and visualizing complex relationships, distributions, and comparisons with minimal code. It builds upon Matplotlib, offering high-level interfaces for functions like scatterplots, heatmaps, and pair plots.

This skill provides zero-shot time series forecasting using Google's TimesFM foundation model. It forecasts any univariate time series (like sales, sensor data, or weather) without requiring custom model training. The model delivers point forecasts along with calibrated prediction intervals (quantiles), offering a robust and probabilistic view of future trends. It is ideal for rapid, reliable forecasting across diverse time-based datasets.

Query gnomAD via GraphQL to retrieve allele frequencies, constraint scores, and loss-of-function annotations for population-informed variant interpretation and rare disease gene prioritization.

Query the GTEx portal and API to retrieve tissue-specific gene expression, eQTL, sQTL, and variant-level regulatory data for interpreting GWAS loci and exploring gene regulation across 54 human tissues.

Query the JASPAR REST API and Python helpers to retrieve TF binding profiles, convert PFMs to PWMs, and scan DNA sequences for high-confidence motifs, enabling regulatory variant interpretation, ChIP/ATAC analysis, and TF network construction.

This skill provides a comprehensive guide to using the Malpedia API for advanced malware intelligence analysis. Users can track malware family relationships, analyze variant evolution, extract associated YARA rules for detection, and map connections to specific threat actors. It is essential for security researchers and SOC analysts building robust threat models.