Skill UI

Conversational research ideation assistant that helps scientists generate novel hypotheses, explore interdisciplinary analogies, challenge assumptions, and outline experiment pathways during early-stage planning.

Probabilistic deep-learning framework built on PyTorch for single-cell omics; handles batch correction, integration, multimodal and spatial data, differential expression, and transfer learning with unified APIs.

A comprehensive guide for systematic statistical analysis, designed for academic research. This skill assists in selecting the correct hypothesis tests (t-test, ANOVA, regression, chi-square), checking assumptions (normality, homogeneity), performing advanced analyses (Bayesian methods, power analysis), calculating effect sizes, and generating full APA-formatted reports for publication.

Statsmodels is a comprehensive Python library dedicated to advanced statistical modeling and econometrics. It provides tools for rigorous statistical inference, including Ordinary Least Squares (OLS), Generalized Linear Models (GLM), mixed-effects models, and time series analysis (ARIMA). Use this skill for detailed diagnostics, coefficient estimation, hypothesis testing, and producing publication-ready statistical reports in fields like econometrics and biostatistics.

TorchDrug is a PyTorch-native toolbox for building graph neural networks tailored to molecules, proteins, and biomedical knowledge graphs, covering property prediction, generation, retrosynthesis, and knowledge graph reasoning with curated datasets and models.

Access DepMap data to fetch CRISPR Chronos dependency scores, drug sensitivity readouts, and gene effect profiles for cancer cell lines, supporting target validation, biomarker discovery, and synthetic-lethality research via API or downloads.

Query gnomAD via GraphQL to retrieve allele frequencies, constraint scores, and loss-of-function annotations for population-informed variant interpretation and rare disease gene prioritization.

Query the GTEx portal and API to retrieve tissue-specific gene expression, eQTL, sQTL, and variant-level regulatory data for interpreting GWAS loci and exploring gene regulation across 54 human tissues.

Query the Monarch Initiative API to explore disease-gene-phenotype associations across species, enabling rare disease gene discovery, phenotype-to-gene mapping, and cross-species modeling via integrated HPO and model organism data.

Provide a comprehensive toolkit for RNA velocity inference in single-cell RNA-seq data, modeling unspliced/spliced kinetics to infer differentiation directions, latent time, and driver genes while complementing Scanpy pipelines.

A comprehensive toolkit for reconstructing and analyzing the evolutionary history of biological sequences (genes, proteins, genomes). The standard workflow includes multiple sequence alignment using MAFFT, robust maximum likelihood tree inference with IQ-TREE 2 and FastTree, and advanced visualization/manipulation using ETE3. This skill is essential for studies in viral phylodynamics, microbial genomics, protein family evolution, and molecular clock dating.

This skill provides deep analytical insights into aggregated family health data. It assesses genetic predisposition, identifies patterns of familial diseases, calculates weighted risk scores based on historical data, and generates personalized, actionable prevention recommendations. Ideal for generating comprehensive family health reports and trend analysis.