Skill UI

Histolab is a specialized Python library for digital pathology research, enabling robust processing of Whole Slide Images (WSI). It automates complex workflows including tissue detection, sophisticated segmentation, and flexible tile extraction from various formats (SVS, TIFF). This tool is crucial for preparing structured, high-quality datasets required for deep learning models and advanced computational pathology analysis.

MarkItDown is a powerful tool designed to convert a wide array of file types—including PDF, DOCX, images, audio, and structured data (JSON/XML)—into clean, token-efficient Markdown format. It supports advanced features like OCR for scanned documents, transcription for audio, and AI-enhanced descriptions, making diverse content readily consumable and structured for modern Language Models and AI pipelines.

Molfeat is a comprehensive Python library designed for molecular featurization. It converts chemical structures (SMILES/RDKit) into numerical feature vectors, supporting over 100 featurizers like ECFP, MACCS, and deep embeddings (ChemBERTa). It unifies featurization pipelines, making it ideal for QSAR modeling, virtual screening, and integrating into deep learning ML workflows.

NeuroKit2 is a comprehensive Python toolkit designed for processing and analyzing diverse physiological biosignals. It covers multiple domains including cardiovascular (ECG, PPG), neural (EEG), autonomic (EDA), respiratory (RSP), and muscular (EMG) signals. Use this skill for advanced psychophysiology research, complex pattern detection, and real-time clinical monitoring applications.

An end-to-end toolkit designed for analyzing high-density Neuropixels electrophysiology recordings. It implements best practices using SpikeInterface, covering the entire workflow: data loading (SpikeGLX, NWB), preprocessing, motion/drift correction, advanced spike sorting (Kilosort4), quality metric computation, and unit curation (including AI-assisted review). Ideal for neuroscience research.

PathML is a comprehensive Python framework designed for computational pathology workflows. It supports end-to-end analysis of Whole Slide Images (WSI), including loading 160+ proprietary formats, performing advanced stain normalization and tissue segmentation, constructing spatial cell graphs, and training deep learning models (e.g., HoVer-Net) for multiplex immunofluorescence and spatial proteomics. Ideal for large-scale biomedical image analysis.

PyHealth is a comprehensive Python toolkit designed for building deep-learning pipelines in the clinical and healthcare domains. It supports diverse data modalities, including EHR records, physiological signals, and medical images. The framework follows a stable 5-stage pipeline (Dataset → Task → Model → Trainer → Metrics), enabling users to perform complex tasks like predicting mortality, optimizing drug recommendations, staging sleep, or cross-mapping medical codes (ICD/ATC/RxNorm) on datasets like MIMIC-III/IV and OMOP.

Qiskit is a leading open-source framework for quantum computing. It enables users to build, optimize, and execute complex quantum circuits and algorithms. The platform supports running on various hardware backends, including IBM Quantum, IonQ, and local simulators. Ideal for advanced research in quantum chemistry simulations, variational quantum algorithms (VQE/QAOA), and quantum machine learning.

A comprehensive, scalable Python toolkit designed for end-to-end single-cell RNA-seq data analysis. It supports crucial steps including quality control (QC), normalization, dimensionality reduction (PCA, UMAP, t-SNE), cell clustering, and differential gene expression analysis. The skill provides ready-to-run scripts for analyzing various formats (e.g., .h5ad, 10X, R-native) and generating publication-quality visualizations and cell type annotations.

scikit-bio is a comprehensive Python library designed for advanced bioinformatics and biological data analysis. It provides robust capabilities for sequence manipulation (DNA, RNA, Protein), performing complex sequence alignments (pairwise and multiple), constructing and analyzing phylogenetic trees, and calculating diverse ecological metrics. It is essential for microbiome analysis, evolutionary studies, and general biological data processing, supporting standard formats like FASTA, Newick, and BIOM.

A comprehensive resource detailing the use of scikit-learn, the industry-standard Python library for classical machine learning. Use this skill for the entire ML lifecycle, including supervised tasks (classification, regression), unsupervised tasks (clustering, dimensionality reduction), data preprocessing, model evaluation, and building production-ready pipelines.

scikit-survival is a comprehensive Python library built on scikit-learn, designed for rigorous time-to-event analysis. It specializes in handling censored data (right, left, or interval-censored) and provides multiple advanced modeling techniques, including Cox proportional hazards models, Random Survival Forests, Gradient Boosting, and Survival SVMs. Users can evaluate model performance using metrics like the Concordance Index and Brier Score, making it ideal for clinical, reliability, and survival research.