Skill UI

PyDESeq2 brings the DESeq2 differential expression workflow to Python, letting users load bulk RNA-seq counts, specify design formulas, fit DESeq2 models, run Wald tests with FDR correction, optionally apply apeGLM shrinkage, and export gene-level statistics within pandas/AnnData pipelines.

PyMC is a powerful Python library for probabilistic programming and advanced Bayesian inference. This comprehensive guide details the full workflow for building, fitting, and validating complex Bayesian models. Learn to implement hierarchical structures, perform MCMC sampling (NUTS), conduct posterior predictive checks (PPC), and effectively quantify uncertainty using industry best practices.

Guides developers through scikit-learn workflows for classical supervised and unsupervised tasks, data preprocessing, evaluation schemes, hyperparameter tuning, and end-to-end pipelines when building interpretable production models.

Toolkit for Python-based survival and time-to-event modeling with scikit-survival, supporting Cox models, ensemble learners, SVMs, and evaluation metrics for censored data.

Statsmodels is a comprehensive Python library dedicated to advanced statistical modeling and econometrics. It provides tools for rigorous statistical inference, including Ordinary Least Squares (OLS), Generalized Linear Models (GLM), mixed-effects models, and time series analysis (ARIMA). Use this skill for detailed diagnostics, coefficient estimation, hypothesis testing, and producing publication-ready statistical reports in fields like econometrics and biostatistics.

TorchDrug is a PyTorch-native toolbox for building graph neural networks tailored to molecules, proteins, and biomedical knowledge graphs, covering property prediction, generation, retrosynthesis, and knowledge graph reasoning with curated datasets and models.

This guide details how to set up and execute large-scale, distributed GPU training jobs on the CoreWeave platform. It covers both single-node multi-GPU setups and multi-node training utilizing PyTorch DDP and Kubernetes resources (A100/H100). This workflow is ideal for fine-tuning large language models (LLMs) or running complex deep learning models that require high-performance, shared-storage compute clusters.

A comprehensive tool for creating high-quality training datasets for custom object detection and segmentation models. It supports multiple advanced annotation methods including BBox drawing, SAM2 pixel-perfect segmentation, and DINOv3 visual grounding. Features include AI auto-detection, object tracking, and standardized COCO format export, streamlining the entire data pipeline from capture to training.

This guide provides a comprehensive reference architecture for building production-ready, enterprise-grade applications on Palantir Foundry. It covers the entire data lifecycle, detailing best practices for the standard data pipeline (Raw > Clean > Model), Ontology design, external API integration patterns, and robust multi-layered security models. Use it when designing, planning, or optimizing complex data infrastructure within Foundry.

Provides a systematic guide for diagnosing and improving poor search quality in vector databases like Qdrant. This guide covers troubleshooting issues such as low recall, when approximate search degrades, selecting optimal embedding models, and correctly tuning HNSW parameters, quantization, and filtering strategies. Essential for optimizing RAG and semantic search pipelines.

Master the creation of robust ELT (Extract, Load, Transform) data pipelines within Snowflake. This guide demonstrates advanced data orchestration using Snowflake Streams for Change Data Capture (CDC), Tasks for scheduled transformations and DAG management, and Dynamic Tables for declarative, auto-refreshing data models. Ideal for building sophisticated, scalable data warehousing solutions.