Skill UI

A powerful Python library that extends pandas to enable complex spatial operations on vector geometric data. It supports reading and writing diverse formats, including Shapefile, GeoJSON, and GeoPackage. Users can perform advanced GIS tasks such as spatial joins, buffering, overlay analysis, calculating areas, managing Coordinate Reference Systems (CRS), and generating interactive choropleth maps, making it essential for geographic data science projects.

This skill proactively detects and reports comprehensive system resources, including CPU cores, GPU types (NVIDIA, AMD, Apple Silicon), available memory, and disk space. It generates a detailed JSON report with strategic, context-aware recommendations for optimizing scientific computing workflows, such as recommending parallel processing libraries (Dask, joblib), out-of-core methods (Zarr), or appropriate GPU acceleration backends (Metal, ROCm). Use this before any large-scale data analysis, model training, or computationally intensive simulation to make informed architectural decisions.

A systematic tool for scientific inquiry, guiding users through the entire research process. It helps formulate testable, mechanistic hypotheses from raw observations or preliminary data, following the established scientific method. The workflow includes comprehensive literature review, evidence synthesis, generating competing explanations, and designing experiments, all while mandating the creation of scientific schematics for visualization.

LaminDB is an open-source, lineage-native lakehouse specifically designed for complex biological datasets and models. It provides unified capabilities for querying, tracking data lineage, validating schemas, and ensuring FAIR compliance across diverse data types (e.g., AnnData, Parquet, Zarr). Use this skill when managing multi-modal genomic data, tracking computational workflows (like Nextflow/Snakemake), or building robust, reproducible data infrastructure in bioinformatics.

Matplotlib is Python's foundational library for creating highly customizable static, animated, and interactive visualizations. It supports various plot types (line, scatter, heatmap, 3D) and offers both pyplot and object-oriented interfaces. Ideal for generating publication-quality scientific charts, complex multi-panel figures, and integrating into notebooks.

This comprehensive skill provides a standardized pipeline for reconstructing the evolutionary history of biological sequences (genes, proteins, genomes). It guides users through essential steps, including multiple sequence alignment using MAFFT, maximum likelihood tree inference with IQ-TREE 2, and visualization with ETE3. Ideal for research in viral phylodynamics, molecular clock studies, and large-scale comparative genomics.

Polars is a lightning-fast DataFrame library built on Apache Arrow for Python. It provides an expression-based API, lazy query optimization, and parallel computation capabilities for efficient data manipulation, analytics, and ETL pipelines. It is designed to handle large, memory-intensive datasets, making it an ideal alternative for migrating from pandas or optimizing complex data workflows.

PyHealth is a comprehensive Python toolkit designed for building deep-learning pipelines in the clinical and healthcare domains. It supports diverse data modalities, including EHR records, physiological signals, and medical images. The framework follows a stable 5-stage pipeline (Dataset → Task → Model → Trainer → Metrics), enabling users to perform complex tasks like predicting mortality, optimizing drug recommendations, staging sleep, or cross-mapping medical codes (ICD/ATC/RxNorm) on datasets like MIMIC-III/IV and OMOP.

scikit-bio is a comprehensive Python library designed for advanced bioinformatics and biological data analysis. It provides robust capabilities for sequence manipulation (DNA, RNA, Protein), performing complex sequence alignments (pairwise and multiple), constructing and analyzing phylogenetic trees, and calculating diverse ecological metrics. It is essential for microbiome analysis, evolutionary studies, and general biological data processing, supporting standard formats like FASTA, Newick, and BIOM.

A comprehensive resource detailing the use of scikit-learn, the industry-standard Python library for classical machine learning. Use this skill for the entire ML lifecycle, including supervised tasks (classification, regression), unsupervised tasks (clustering, dimensionality reduction), data preprocessing, model evaluation, and building production-ready pipelines.

scVelo is a powerful Python package designed for RNA velocity analysis using single-cell RNA-seq data. It estimates cell state transitions by modeling the kinetics of mRNA splicing—specifically using the ratio of unspliced to spliced mRNA abundances. This allows researchers to reconstruct developmental trajectories and predict cell fates, even when only snapshot data is available, making it a vital complement to standard trajectory inference tools like Scanpy.

This skill utilizes the TimesFM foundation model for zero-shot forecasting of any univariate time series. It predicts future values with calibrated probabilistic intervals without requiring custom model training. It includes a mandatory preflight system checker to ensure adequate RAM, GPU, and disk resources for safe, local inference across various data types (sales, sensor, energy).