Skill UI

Polars is a lightning-fast DataFrame library built on Apache Arrow for Python. It provides an expression-based API, lazy query optimization, and parallel computation capabilities for efficient data manipulation, analytics, and ETL pipelines. It is designed to handle large, memory-intensive datasets, making it an ideal alternative for migrating from pandas or optimizing complex data workflows.

A high-performance library built on Polars for advanced genomic interval operations and bioinformatics file I/O. It provides robust support for core interval arithmetic (overlap, merge, complement) and reading/writing major formats like VCF, BAM, BED, and GFF. Features include out-of-core streaming, cloud-native I/O (S3, GCS, Azure), and a powerful SQL interface, making it ideal for large-scale genomic research.