Skill UI

Access the BRENDA SOAP API to retrieve enzyme kinetic parameters, reaction equations, organism-specific data, and environmental preferences, enabling biochemical research, metabolic pathway reconstruction, and enzyme engineering workflows.

RDKit delivers a Python-based cheminformatics toolkit for parsing SMILES/SDF, computing descriptors, generating 2D/3D coordinates, fingerprinting, searching substructures, managing reactions, and visualizing molecules, ideal for drug discovery and computational chemistry workflows.

Query the Reactome Content and Analysis Services (or the reactome2py client) to fetch pathway hierarchies, map genes, run overrepresentation/expression analyses, and explore disease interactions for systems biology research.

COBRApy is a powerful Python library for Constraint-Based Reconstruction and Analysis (COBRA). It enables deep dives into cellular metabolism, allowing users to build, simulate, and analyze complex metabolic models (e.g., genome-scale models). Core functionalities include Flux Balance Analysis (FBA), Flux Variability Analysis (FVA), performing gene/reaction knockouts, and optimizing growth media. It supports standard metabolic model formats like SBML, JSON, and YAML.

This comprehensive guide details the process of implementing a secure and robust system for handling Palantir Foundry webhook events. It covers key steps including API-based webhook registration, mandatory signature verification with replay protection, sophisticated event routing for various object lifecycles (create, update, delete), and ensuring idempotent processing using caching mechanisms like Redis. Use this when external microservices must react reliably and immediately to changes within the Foundry Ontology or data assets.

A comprehensive tool for performing pathway and gene-set enrichment analysis (GSEA, ORA, ssGSEA, GSVA). Used in computational biology to determine which biological pathways or gene sets are significantly over-represented in a given list of genes or ranked gene data. Supports multiple databases (GO, KEGG, Reactome, MSigDB) and provides tools for result interpretation, visualization, and publication-ready reporting.