Skill UI

This technique guides users to use precise chemical compound names, specific concentration values (e.g., "1.5 mg/L"), and taxonomic synonym counts as exact-match search anchors when querying biological literature. By leveraging quotation marks and combining multiple specific terms, it uniquely identifies research papers or species details, greatly improving search precision in biochemistry and botany.

This advanced research technique is designed for deep dives into football topics. Instead of relying solely on the original query, it mandates tracking every discovered entity—such as player names, club names, or coaches—from search results. By treating these entities as new leads, the user must formulate follow-up searches using the discovered names and remaining constraints, ensuring nothing relevant is overlooked and building a comprehensive knowledge chain.

This technique guides users on how to construct highly specific search queries for academic papers. Instead of relying solely on broad topic keywords, users should prioritize combining concrete numerical identifiers—such as exact sample sizes, population percentages, concentration levels, or specific year ranges—with methodological terms and discipline keywords. Using these numerical anchors significantly increases the uniqueness and precision of the search results, helping to pinpoint the exact study required.

Provides programmatic access to massive, versioned public single-cell and spatial transcriptomics datasets from CZ CELLxGENE. This skill allows users to efficiently query specific subsets of cell metadata, gene expression matrices, embeddings, and summary statistics across various organisms, tissues, and diseases. It is ideal for large-scale, memory-efficient biological research and model training without full dataset downloads.

DeepChem is a comprehensive Python library designed for applying machine learning to complex fields like chemistry, materials science, and biology. It enables users to perform molecular property prediction (e.g., ADMET, toxicity), train models using specialized graph neural networks (GNNs), and process diverse molecular formats (SMILES, SDF, FASTA). It provides extensive featurization options, making it foundational for drug discovery and computational chemistry research.

A systematic tool for scientific inquiry, guiding users through the entire research process. It helps formulate testable, mechanistic hypotheses from raw observations or preliminary data, following the established scientific method. The workflow includes comprehensive literature review, evidence synthesis, generating competing explanations, and designing experiments, all while mandating the creation of scientific schematics for visualization.

Perform comprehensive molecular dynamics (MD) simulations using high-performance engines like OpenMM and analysis tools like MDAnalysis. This skill allows users to model the time evolution of biological systems, covering system preparation (solvation, force field assignment), energy minimization, NVT equilibration, and advanced analysis (RMSD, free energy surfaces). Ideal for structural biology, drug binding studies, and biophysics research.

This skill provides a comprehensive Python API integration for the OMERO platform, an open-source solution for managing and analyzing large-scale microscopy datasets. Users can programmatically access images, retrieve structured data, analyze raw pixel data, manage complex annotations (ROIs), and execute batch processing workflows essential for high-content screening and advanced biological research.

This comprehensive skill provides a standardized pipeline for reconstructing the evolutionary history of biological sequences (genes, proteins, genomes). It guides users through essential steps, including multiple sequence alignment using MAFFT, maximum likelihood tree inference with IQ-TREE 2, and visualization with ETE3. Ideal for research in viral phylodynamics, molecular clock studies, and large-scale comparative genomics.

Qiskit is a leading open-source framework for quantum computing. It enables users to build, optimize, and execute complex quantum circuits and algorithms. The platform supports running on various hardware backends, including IBM Quantum, IonQ, and local simulators. Ideal for advanced research in quantum chemistry simulations, variational quantum algorithms (VQE/QAOA), and quantum machine learning.

QuTiP is a powerful Python library designed for simulating and analyzing quantum mechanical systems. It provides comprehensive tools to model both closed (unitary) and open (dissipative) quantum dynamics. Users can study complex phenomena like decoherence, quantum optics, and master equations. The library supports various time evolution solvers, calculating entanglement, entropy, and visualizing quantum states on the Bloch sphere or in phase space. Ideal for theoretical physics research and academic simulations.

This skill provides a systematic framework for evaluating the rigor of scientific claims, research methodology, and evidence quality. It guides users through assessing experimental design validity, identifying various types of biases (e.g., selection, cognitive), and applying established grading frameworks like GRADE or Cochrane Risk of Bias. Ideal for systematic reviews, peer review, and critical analysis of scientific literature.