Skill UI

Query NCBI ClinVar for variant clinical significance, mixing gene/condition searches, API/FTP downloads, and VCF annotations to support genomic medicine interpretation workflows.

Query the PrimeKG precision medicine knowledge graph to explore genes, drugs, diseases, phenotypes, and their relationships, supporting drug discovery, repurposing, and phenotype analysis through programmatic scripts.

PrimeKG is a comprehensive knowledge graph integrating over 20 primary databases to map complex biological relationships. It allows users to query multiscale data, including genes, drugs, diseases, and phenotypes. Ideal for drug discovery, identifying repurposing opportunities, and analyzing deep disease contexts in network pharmacology.

This skill guides authors through evaluating the suitability of their clinical research manuscript for Annals of Internal Medicine. It provides deep insights into the journal's high standards, including specific methodological requirements (CONSORT, PRISMA, STROBE, STARD, TRIPOD), required evidence synthesis depth, ideal scope (RCTs, systematic reviews, guidelines), and current house style guidelines necessary for successful submission.

This guide outlines the rigorous academic requirements for submissions to the China Sport Science journal. It covers both natural sciences (physiology, biomechanics, exercise medicine) and social sciences (sports sociology, policy, management). Submissions must address core sport science ontology problems with high methodological rigor, ensuring the contribution is central to the field, rather than merely applying other disciplines.

This resource provides a comprehensive fit-check and framing guide for submitting research to Critical Care Medicine, the flagship journal of SCCM. It outlines the high academic and clinical bar required for studies on the critically ill, covering necessary focus on clinically important advances, adherence to specific reporting guidelines (e.g., CONSORT, STROBE), and rigorous methodological expectations for ICU-related research.

This comprehensive guide helps researchers evaluate whether a clinical or health-services study is appropriate for publication in JAMA Internal Medicine. It details the journal's high bar for methodological rigor, including requirements for randomized trials (CONSORT), observational studies (STROBE), and systematic reviews (PRISMA). It covers everything from study design and statistical reporting to addressing potential desk-reject triggers, ensuring authors submit high-quality, impactful research.

This guide provides criteria for submitting research to the Journal of Tianjin University of Sport. The journal highly values mechanism-driven studies in exercise physiology, biochemistry, biomechanics, and sports medicine. Submissions must demonstrate rigorous experimental design, detailed measurements, statistical validity, and clear mechanistic interpretation, moving beyond simple descriptive reports.

This skill provides comprehensive guidance for authors submitting manuscripts to Nature Medicine. It assesses the fit of research that bridges basic biological mechanisms to clear clinical applications (translational medicine). It details highly rigorous requirements, including the need for convergent evidence, specific reporting standards (CONSORT, TRIPOD-AI), and structural guidelines necessary for publishing high-impact translational science.

This skill provides a comprehensive framework for evaluating whether a clinical medicine or global-health manuscript is suitable for publication in The Lancet. It guides authors on refining the manuscript's framing, ensuring methodological rigor (e.g., PRISMA, STROBE), and adhering to the journal's specific house style and high editorial standards related to global health and health equity.

This skill provides comprehensive guidance for submitting high-impact clinical and population research to The Lancet Respiratory Medicine. It details the journal's specialized scope, which favors practice-changing randomized trials and major prospective cohorts in respiratory and critical care. The guide highlights the rigorous evidence bar, including expected reporting guidelines (CONSORT, STROBE, PRISMA), statistical rigor, and structural house style, serving as a crucial fit and framing aid for authors.