Skill UI

A comprehensive guide to modern backend development patterns for scalable server-side applications using Node.js, Express, and Next.js. Covers API design (RESTful), data access patterns (Repository, Service Layer), database optimization (N+1 prevention, Transactions), and advanced caching strategies (Redis, Cache-Aside). Essential for building robust, high-performance APIs.

A comprehensive reference guide for structuring development projects within the Cursor IDE. It details best practices for directory layout, defining layered rules (covering global conventions, security constraints, and technology-specific patterns like API routes and database access), and optimizing indexing strategies. This ensures maximum AI effectiveness, improves code maintainability, and streamlines the entire development workflow.

This skill details best practices for handling and structuring Evernote data. It covers designing local database schemas (SQL), advanced ENML content processing (to Markdown/HTML), managing attachments, and implementing reliable incremental synchronization using Update Sequence Numbers (USN). Ideal for developers building robust applications requiring deep, local data access and integrity checks for Evernote content.

Implements robust Role-Based Access Control (RBAC) for Juicebox, an AI-powered platform for recruiting and sales. This system defines granular permissions for various roles (Admin, Recruiter, Analyst, etc.), controlling access to sensitive candidate databases, data enrichment capabilities, outreach functions, and data export. It ensures data governance, maintains compliance (e.g., SOC 2), and segments user access based on job function and need-to-know principles.

Comprehensive guide to managing data securely in Replit applications. This skill covers three core storage systems: PostgreSQL for structured data and complex queries; Replit KV Database for caching and session management; and Object Storage for file uploads and blobs. Learn best practices including parameterized queries, TTL implementation, and secure data access patterns.

This guide provides production-ready coding patterns for interacting with various built-in Replit services. It covers best practices for setting up singleton clients, implementing robust error handling, and creating type-safe wrappers for Key-Value Database, Object Storage, PostgreSQL, and Auth middleware. Ideal for developers building complex Replit integrations or establishing standardized data access layers.

A comprehensive guide to implementing secure secrets management practices for Continuous Integration/Continuous Deployment (CI/CD) pipelines. It covers using industry-leading tools like HashiCorp Vault, AWS Secrets Manager, Azure Key Vault, and GCP Secret Manager to securely store, retrieve, and automatically rotate credentials (API keys, database passwords, TLS certificates) without hardcoding them into source code. Includes best practices for least-privilege access and audit logging.

Retrieve AlphaFold’s AI-predicted protein models via UniProt IDs, download CIF/PDB coordinates, inspect confidence metrics, and feed them into structural analysis or drug-discovery pipelines.

Biopython provides Python APIs for sequence manipulation, database access, BLAST automation, structural bioinformatics, and phylogenetics, making it ideal for scripting custom pipelines and batch processing in computational molecular biology workflows.

Access the BRENDA SOAP API to retrieve enzyme kinetic parameters, reaction equations, organism-specific data, and environmental preferences, enabling biochemical research, metabolic pathway reconstruction, and enzyme engineering workflows.

Access the ClinicalTrials.gov API v2 to search trials by condition, drug, location, sponsor or status, fetch details via NCT ID, and export JSON/CSV data for research analysis, patient matching, and trial monitoring.

Provide REST API access to ClinPGx, the successor to PharmGKB, for querying gene-drug interactions, CPIC/DPWG/FDA guidelines, allele functions, and evidence that supports precision dosing and pharmacogenomics-driven clinical decisions.