Skill UI

Access DepMap data to fetch CRISPR Chronos dependency scores, drug sensitivity readouts, and gene effect profiles for cancer cell lines, supporting target validation, biomarker discovery, and synthetic-lethality research via API or downloads.

Medchem Filtering Toolkit is a Python library offering drug-likeness heuristics, structural alert and PAINS filters, group detection, catalogs, and complexity scoring to triage compound libraries and prioritize leads in drug discovery workflows.

Query the PrimeKG precision medicine knowledge graph to explore genes, drugs, diseases, phenotypes, and their relationships, supporting drug discovery, repurposing, and phenotype analysis through programmatic scripts.

Provides AI-ready drug discovery datasets, splits, and benchmarks covering ADME, toxicity, DTI, DDI, and molecular generation so researchers can train, compare, and optimize therapeutic ML models with curated splits and oracles.

RDKit delivers a Python-based cheminformatics toolkit for parsing SMILES/SDF, computing descriptors, generating 2D/3D coordinates, fingerprinting, searching substructures, managing reactions, and visualizing molecules, ideal for drug discovery and computational chemistry workflows.