Skill UI

This skill guides authors on assessing if their cardiovascular manuscript meets the rigorous standards of Circulation, the AHA's flagship journal. It covers the journal's specific scope, ideal research methods (e.g., RCTs, biomarker studies, epidemiology), structural requirements, and how to effectively frame the work to impact AHA guidelines and clinical practice.

This comprehensive guide helps authors assess the suitability of their diabetes or metabolic manuscript for *Diabetes Care* (ADA). It details the required clinical scope, evidence strength (e.g., RCTs, observational studies), necessary data analysis standards, and specific structural requirements, ensuring the work aligns with high-impact clinical practice guidelines and the ADA Standards of Care.

This skill provides a comprehensive fit and formatting guide for submitting high-impact clinical and surgical research to European Urology. It assesses the study's required evidence level, adherence to specific reporting guidelines (e.g., CONSORT, STROBE), and alignment with EAU/Elsevier house style. It is a vital aid for authors needing to re-frame their work for optimal journal acceptance.

A comprehensive heuristic tool and guide for authors targeting JAMA. It assesses manuscript fit, methodological rigor (including adherence to CONSORT, PRISMA, STROBE guidelines), structured abstract formatting, and the latest AMA house style. Use this before submitting a high-impact clinical or scientific manuscript to ensure compliance with top-tier journal standards.

A comprehensive guide for academic authors detailing mandatory compliance requirements for high-impact publications. This checklist covers essential elements such as prospective clinical trial registration, IRB/ethics approval statements, obtaining informed consent, adhering to ICMJE authorship criteria, disclosing conflicts of interest, and providing detailed data-sharing plans. Use this when preparing a manuscript for submission to major medical journals.

This comprehensive guide helps researchers evaluate whether a clinical or health-services study is appropriate for publication in JAMA Internal Medicine. It details the journal's high bar for methodological rigor, including requirements for randomized trials (CONSORT), observational studies (STROBE), and systematic reviews (PRISMA). It covers everything from study design and statistical reporting to addressing potential desk-reject triggers, ensuring authors submit high-quality, impactful research.

This guide provides a structured checklist and framework for researchers to assess whether their clinical study meets the general-medical-importance bar of top-tier journals, such as JAMA. It helps authors determine if their findings are broadly relevant to practicing clinicians, if the evidence level is sufficient, and if the article type matches the journal's requirements, preventing premature submission.

A comprehensive guide for authors preparing medical manuscripts for high-impact journals. It outlines rigorous standards for statistical reporting, emphasizing the use of effect sizes with 95% Confidence Intervals (CIs) over p-values alone. Key topics include pre-specification, intention-to-treat analysis, multiplicity control, handling missing data through imputation, and reporting both relative and absolute effects to ensure maximum statistical rigor and reproducibility.

This tool acts as a workflow router for preparing clinical manuscripts for high-impact journals like JAMA. It does not replace specialized writing or analysis skills but guides the user through the correct, sequential stages—from initial scope assessment to final submission and revision—ensuring all necessary standards (e.g., EQUATOR, CONSORT) are addressed in the proper order.

This skill helps authors assess the suitability of their translational or mechanistic manuscript for the Journal of Clinical Investigation (JCI). It provides detailed guidance on meeting JCI's high standards, emphasizing primary evidence from human clinical samples, clear mechanistic insight into disease, and appropriate framing. Use this tool when targeting JCI or when needing to select the most appropriate high-impact scientific venue.

A comprehensive guide for authors targeting high-impact hepatology journals, such as the Journal of Hepatology. It assesses the fit of liver-disease studies, outlines the required evidence bar (e.g., powered clinical endpoints, biomarker validation), and details mandatory reporting guidelines (CONSORT, STROBE, PRISMA). This skill aids in manuscript re-framing and ensures compliance with EASL/Elsevier house styles before submission.

A rigorous pre-writing framework used by researchers to stress-test a study's significance against the high standards of top-tier medical journals (e.g., The Lancet). It assesses whether the work is clinically important, globally relevant, likely to change policy, and addresses health equity, preventing wasted research efforts on unsuitable manuscripts.