Skill UI

A comprehensive guide for designing and managing document control systems for ISO 13485-compliant Quality Management Systems (QMS), specifically tailored for the medical device industry. This resource covers document numbering, version control, change management workflows, approval processes, and ensures compliance with rigorous standards like 21 CFR Part 11, including electronic signatures and audit trails.

Implements and maintains ISO 13485 QMS for medical device organizations, covering gap analysis, documentation control, internal audits, supplier qualification, and CAPA tracking to keep regulatory programs audit-ready.

This model provides an engineering operational framework for teams that leverage AI agents to generate large volumes of code. It shifts the focus from simple syntax to process quality, robust architecture design, rigorous testing, and systematic risk control, ensuring the development of highly stable and reliable systems in AI-assisted environments.

This pattern defines a robust, continuous loop structure for autonomous agents. It integrates crucial components like quality gates, evaluation harnesses, and explicit recovery controls. It guides complex workflows by defining decision paths (e.g., PR control, RFC decomposition) and includes strategies to mitigate common failure modes such as infinite loop churn or cost drift, ensuring measurable progress in autonomous systems.

This guide outlines a systematic process for transforming any recurring technical pattern, complex debugging solution, or workflow into a standalone, portable skill. It details the multi-step extraction workflow, including pattern identification, structured documentation generation (SKILL.md), and quality control checks to ensure the skill can be reused across different projects.

This advanced pipeline orchestrates complex feature development based on Request for Comments (RFCs). It breaks down monolithic changes into small, independently verifiable work units, managing dependencies through a Directed Acyclic Graph (DAG). It includes multiple quality gates, dedicated unit testing, and a safe merge queue to ensure robust integration and controlled deployment.

Provides an expert methodology to significantly reduce AI API spending (40-80%) without sacrificing user quality. The guide covers cost auditing, optimizing existing systems, and designing cost-efficient architectures using techniques like model routing, prompt caching, output length control, and prompt compression.

This advanced skill automates the enforcement of Python code quality using Ruff. It implements a controlled, iterative workflow that supports safe and unsafe automatic autofixes, formats the code, and reviews diffs after each pass. The process recursively repeats until all findings are resolved or require explicit user decision, ensuring high code consistency and quality gates.

DeepTools is a comprehensive command-line toolkit for processing and analyzing high-throughput sequencing data. It supports workflows for ChIP-seq, RNA-seq, ATAC-seq, and other NGS experiments. Core capabilities include converting BAM files to normalized coverage tracks (bigWig), performing quality control (QC), sample correlation analysis, and generating publication-quality visualizations, such as heatmaps and profile plots across genomic regions.

A comprehensive, scalable Python toolkit designed for end-to-end single-cell RNA-seq data analysis. It supports crucial steps including quality control (QC), normalization, dimensionality reduction (PCA, UMAP, t-SNE), cell clustering, and differential gene expression analysis. The skill provides ready-to-run scripts for analyzing various formats (e.g., .h5ad, 10X, R-native) and generating publication-quality visualizations and cell type annotations.

A comprehensive guide for scaling Claude usage in high-throughput, enterprise-level applications. Learn four advanced strategies, including Message Batches for bulk processing, using p-limit for concurrency control, managing rate limit tier upgrades, and selecting the optimal model (e.g., Haiku) to balance speed and quality.

This advanced skill performs a zero-context, multi-layered verification of every bibliographic citation within an academic manuscript. It checks for the existence of cited works, verifies the correctness of metadata (authors, years, venues), and, crucially, ensures the cited paper actually supports the claim it is used for. Essential for pre-submission quality control.