Skill UI

DeepChem is a comprehensive Python library designed for applying machine learning to complex fields like chemistry, materials science, and biology. It enables users to perform molecular property prediction (e.g., ADMET, toxicity), train models using specialized graph neural networks (GNNs), and process diverse molecular formats (SMILES, SDF, FASTA). It provides extensive featurization options, making it foundational for drug discovery and computational chemistry research.

DeepTools is a comprehensive command-line toolkit for processing and analyzing high-throughput sequencing data. It supports workflows for ChIP-seq, RNA-seq, ATAC-seq, and other NGS experiments. Core capabilities include converting BAM files to normalized coverage tracks (bigWig), performing quality control (QC), sample correlation analysis, and generating publication-quality visualizations, such as heatmaps and profile plots across genomic regions.

This skill provides programmatic access to the Cancer Dependency Map (DepMap), a comprehensive resource characterizing genetic dependencies in cancer cell lines. Use it to identify genes essential for specific cancer types, discover synthetic lethal interactions, and validate potential oncology drug targets using CRISPR and RNAi data.

This advanced tool utilizes the Digital Human DNA (DHDNA) framework to extract a comprehensive cognitive signature from any piece of text. It analyzes the author's unique thinking patterns, reasoning methods, decision-making styles, and core values across 12 detailed dimensions (e.g., Analytical Depth, Ethical Reasoning, Emotional Processing). It provides a structured profile, revealing the topology of the mind behind the writing, without judgment.

DiffDock is a cutting-edge deep learning tool leveraging diffusion models to predict the 3D binding poses of small molecule ligands to protein targets. It supports structure-based drug discovery, enabling single-complex docking, batch virtual screening, and lead optimization. Users can input protein structures (PDB) or sequences, along with diverse ligand formats (SMILES, SDF, MOL2). The tool outputs predicted poses and confidence scores, making it crucial for identifying potential drug candidates, though it does not predict binding affinity.

A comprehensive toolkit for developing and executing genomics pipelines on the DNAnexus cloud platform. It provides capabilities for app/applet building, managing large biomedical datasets (FASTQ, BAM, VCF), orchestrating complex workflows, and interacting programmatically using the dxpy Python SDK.

The ESM skill provides comprehensive tools for computational biology, leveraging ESM3 and ESM-C models. It enables sophisticated protein sequence generation, structure prediction (sequence to 3D structure), inverse folding (structure to sequence design), and generating function-conditioned proteins. Use it for de novo protein design, feature embedding, and advanced structural analysis in bioinformatics workflows.

ETE is a comprehensive toolkit for phylogenomic research, designed to handle and analyze hierarchical tree structures. It supports various tree formats (Newick, NHX) and provides advanced functionalities such as detecting evolutionary events (duplication/speciation), identifying orthologs/paralogs, integrating with NCBI taxonomy for lineage tracking, and generating publication-quality visualizations in PDF/SVG.

This skill performs comprehensive Exploratory Data Analysis (EDA) on specialized scientific datasets. It supports over 200 file formats across diverse domains, including chemistry (PDB), bioinformatics (FASTA, BAM), microscopy (TIFF), and spectroscopy. The system automatically detects the file type, assesses data quality and integrity, and generates detailed, format-specific markdown reports, providing deep insights and recommending downstream analyses.

A lightweight Python library designed for reading, parsing, and writing Flow Cytometry Standard (FCS) files. It extracts event data as NumPy arrays, handles complex metadata, and supports multiple FCS versions (2.0-3.1). Ideal for data preprocessing, building cytometry pipelines, and inspecting experimental results.

FluidSim is an object-oriented Python framework for high-performance Computational Fluid Dynamics (CFD) simulations. It provides specialized solvers for complex equations like 2D/3D Navier-Stokes, shallow water, and stratified flows. Utilizing pseudospectral methods with FFT, the framework supports parallel computing (MPI) and offers a complete workflow, including parameter configuration, simulation execution, and advanced post-processing and visualization.

This skill allows users to generate and edit high-quality, general-purpose images using advanced AI models like FLUX.2 and Gemini. It is suitable for creating photorealistic images, artistic illustrations, concept art, marketing visuals, and general visual assets. Note that this tool is designed for creative content, not technical schematics or diagrams.