Skill UI

Query NCBI ClinVar for variant clinical significance, mixing gene/condition searches, API/FTP downloads, and VCF annotations to support genomic medicine interpretation workflows.

This skill provides a comprehensive guide for adapting research manuscripts for the American Journal of Respiratory and Critical Care Medicine (AJRCCM). It assesses a study's scientific fit across the spectrum of basic science, translational research, and clinical trials. It ensures adherence to rigorous reporting guidelines (e.g., CONSORT, STROBE, ARRIVE) and the journal's specific house style, helping authors significantly improve their submission readiness.

A comprehensive guide for authors targeting Anesthesiology, outlining the journal's scope, which includes perioperative medicine, pain management, and critical care. It details the rigorous expectations for clinical trials, requiring prespecified outcomes, proper registration (e.g., CONSORT, STROBE), and clinically meaningful advancements. This skill helps authors re-frame their research to meet the high methodological and scientific standards of the journal.

This skill guides authors through evaluating the suitability of their clinical research manuscript for Annals of Internal Medicine. It provides deep insights into the journal's high standards, including specific methodological requirements (CONSORT, PRISMA, STROBE, STARD, TRIPOD), required evidence synthesis depth, ideal scope (RCTs, systematic reviews, guidelines), and current house style guidelines necessary for successful submission.

This skill provides a comprehensive pre-submission review for manuscripts targeting Cell Reports Medicine. It assesses the manuscript's fit regarding scope (translational and clinical research with mechanistic depth), evidence bar (requiring strong validation and causality), and house style. It helps authors determine if their work aligns with the journal's requirements before official submission.

This resource provides a comprehensive fit-check and framing guide for submitting research to Critical Care Medicine, the flagship journal of SCCM. It outlines the high academic and clinical bar required for studies on the critically ill, covering necessary focus on clinically important advances, adherence to specific reporting guidelines (e.g., CONSORT, STROBE), and rigorous methodological expectations for ICU-related research.

A comprehensive workflow guide for routing clinical medicine manuscripts. It classifies studies by specialty, study design (RCT, observational, review), and evidence strength, helping authors select the optimal journal venue (e.g., JAMA, Lancet) for submission and re-framing. It emphasizes matching the manuscript to specialized society guidelines and evidence hierarchy.

This comprehensive guide helps researchers evaluate whether a clinical or health-services study is appropriate for publication in JAMA Internal Medicine. It details the journal's high bar for methodological rigor, including requirements for randomized trials (CONSORT), observational studies (STROBE), and systematic reviews (PRISMA). It covers everything from study design and statistical reporting to addressing potential desk-reject triggers, ensuring authors submit high-quality, impactful research.

This skill provides comprehensive guidance for authors submitting manuscripts to Nature Medicine. It assesses the fit of research that bridges basic biological mechanisms to clear clinical applications (translational medicine). It details highly rigorous requirements, including the need for convergent evidence, specific reporting standards (CONSORT, TRIPOD-AI), and structural guidelines necessary for publishing high-impact translational science.

Provides a comprehensive guide for authors targeting The New England Journal of Medicine (NEJM). It outlines the journal's stringent editorial standards, including the required evidence bar, structured abstract formatting, and best practices for clinical manuscript submission, helping authors gauge manuscript fit and preparation needs.

This skill acts as a central router for manuscripts targeting The New England Journal of Medicine (NEJM). It does not replace specialized skills but rather diagnoses the current stage of a clinical manuscript—from initial significance testing to response to reviewers—and directs the user to the correct subsequent skill (e.g., nejm-fit, nejm-study-design). It outlines the rigorous workflow, necessary checks, and structural differences required for submission to top-tier clinical journals.

A comprehensive guide for authors targeting PLOS Medicine. It outlines the journal's scope, required methodological rigor (e.g., CONSORT, STROBE), house style, and essential pre-submission checks. Use this when assessing if a clinical, public health, or epidemiological manuscript meets the journal's high open-access standards.