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ChEMBL Bioactivity Query

chembl-database

K-Dense-AI/claude-scientific-skills

Programmatically query ChEMBL bioactive molecules, targets, and approved drugs via the Python client; filter by structure, properties, activities, and indications to support inhibitor hunting or SAR studies for medicinal chemistry.

Clinical Trials Database

clinicaltrials-database

K-Dense-AI/claude-scientific-skills

Access the ClinicalTrials.gov API v2 to search trials by condition, drug, location, sponsor or status, fetch details via NCT ID, and export JSON/CSV data for research analysis, patient matching, and trial monitoring.

ClinPGx Database Access

clinpgx-database

K-Dense-AI/claude-scientific-skills

Provide REST API access to ClinPGx, the successor to PharmGKB, for querying gene-drug interactions, CPIC/DPWG/FDA guidelines, allele functions, and evidence that supports precision dosing and pharmacogenomics-driven clinical decisions.

ClinVar Variant Explorer

clinvar-database

K-Dense-AI/claude-scientific-skills

Query NCBI ClinVar for variant clinical significance, mixing gene/condition searches, API/FTP downloads, and VCF annotations to support genomic medicine interpretation workflows.

COSMIC Mutation Access

cosmic-database

K-Dense-AI/claude-scientific-skills

Programmatic access to the COSMIC cancer mutation database for downloading mutations, Cancer Gene Census, mutational signatures, fusions, copy number, expression, and resistance data to fuel oncology research or bioinformatics pipelines after authentication.

DrugBank Database Insights

drugbank-database

K-Dense-AI/claude-scientific-skills

Provides programmatic access to DrugBank drug and target data, covering downloads, queries, interaction networks, targets/pathways, and chemical similarity analyses for pharmacology research and safety reviews.

ENA Sequence Access

K-Dense-AI/claude-scientific-skills

Access the European Nucleotide Archive via REST/FTP to fetch DNA/RNA sequences, raw reads, assemblies, annotations, and taxonomy for research or bioinformatics pipelines.

Ensembl Genome API

ensembl-database

K-Dense-AI/claude-scientific-skills

Query Ensembl’s RESTful API to access gene annotations, sequences, variants, orthologs, and assembly mappings across 250+ species, enabling integration into genomic research pipelines.

FDA Regulatory Data Access

K-Dense-AI/claude-scientific-skills

Provides Python access to openFDA endpoints for drugs, devices, foods, veterinary products, and substances, enabling regulatory analysis, safety monitoring, recalls tracking, and pharmacovigilance research.

NCBI Gene Explorer

K-Dense-AI/claude-scientific-skills

Access NCBI Gene data via E-utilities or Datasets API to look up genes by symbol or ID, retrieve RefSeqs, GO terms, chromosomal locations, phenotypes, and run batch workflows for annotation pipelines.

GEO Data Retriever

K-Dense-AI/claude-scientific-skills

Connect to NCBI's GEO repository, search series/samples/platforms via Entrez queries, fetch profiles, and download raw/processed matrices using GEOparse for transcriptomics and expression analysis workflows.

Unified Bioinformatics Query

K-Dense-AI/claude-scientific-skills

gget is a CLI/Python client that unifies querying over 20+ bioinformatics databases, letting researchers fetch gene info, sequences, BLAST results, structures, and enrichment data interactively or within scripts.

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