Skill UI

Query the JASPAR REST API and Python helpers to retrieve TF binding profiles, convert PFMs to PWMs, and scan DNA sequences for high-confidence motifs, enabling regulatory variant interpretation, ChIP/ATAC analysis, and TF network construction.

Query the Monarch Initiative API to explore disease-gene-phenotype associations across species, enabling rare disease gene discovery, phenotype-to-gene mapping, and cross-species modeling via integrated HPO and model organism data.

This comprehensive guide facilitates the development of a production-ready Minimum Viable Product (MVP) for a SaaS business. It covers the entire lifecycle, including idea validation, modern tech stack selection (Next.js, Supabase, Stripe), architectural design for multi-tenancy, database schema planning, authentication setup, payment integration, and a detailed pre-launch checklist for technical and marketing readiness.

Provides instant, temporary Postgres databases for local development, prototyping, and testing environments. Supports connecting via REST API, CLI, SDK, and even Vite plugins. No account or credit card is required, making it ideal for setting up quick, throwaway database instances for development purposes.

A specialized review tool for identifying critical performance bottlenecks within Django applications. It focuses on validating issues such as N+1 queries, unbounded querysets, missing database indexes, and write loops. Use this when you suspect database slowdowns or memory exhaustion due to inefficient ORM usage, ensuring findings are provable and actionable.

This expert assists developers in building type-safe, high-performance database layers using Drizzle ORM with TypeScript. It provides deep knowledge of schema design, complex relational querying (joins, aggregations), managing migrations via Drizzle Kit, and seamless integration with modern stacks like Next.js, tRPC, and serverless environments. Ideal for developers needing a zero-overhead, type-safe ORM alternative.

A comprehensive guide detailing how to use API routes in Expo Router with EAS Hosting. Learn best practices for handling server-side secrets, proxying third-party APIs (e.g., OpenAI, Stripe), performing database operations, and implementing robust backend logic using standard HTTP methods (GET, POST, etc.). Ideal for building secure, scalable mobile application backends.

This skill provides comprehensive functionality for querying, comparing, and calculating nutritional data from a structured food database. Users can perform precise searches by food name or nutritional criteria (e.g., high protein, low GI). It supports calculating total nutrient intake based on specific portions, suggesting foods for various health conditions (like diabetes or high blood pressure), and performing detailed comparative analysis between multiple food items.

This skill generates a complete, opinionated, modern full-stack Rails application boilerplate. It sets up a robust tech stack including Rails 8, PostgreSQL, React, Inertia.js, Vite, Tailwind CSS, Sidekiq, and Redis. Designed for developers who need a starting point that adheres to best practices for database structure (UUIDs, JSONB), background job processing, comprehensive testing, and modern frontend development (TSX). Ideal for bootstrapping complex, production-grade web services.

A comprehensive guide and methodology for identifying, measuring, and fixing performance bottlenecks across the entire stack. This skill covers optimizing database queries (e.g., N+1 problems, missing indexes), improving API efficiency (caching, parallel processing), and enhancing frontend performance (memoization, code splitting, image optimization). It emphasizes the critical 'Measure First' principle to ensure all optimizations are data-driven and effective.

Comprehensive guide to LLM Operations (LLMOps). Covers advanced topics like Retrieval-Augmented Generation (RAG), vector database management (Pinecone, Chroma), embeddings, fine-tuning, prompt engineering, and cost optimization. Essential for bridging the gap between AI prototypes and reliable, scalable, production-grade AI systems.

This comprehensive index covers 37 advanced engineering skills designed for complex system architecture, platform operations, and reliability. Skills include agent design, RAG implementation, CI/CD, observability, database modeling, and security auditing, supporting the entire development lifecycle for powerful enterprise applications.