Skill UI

Provide REST API access to ClinPGx, the successor to PharmGKB, for querying gene-drug interactions, CPIC/DPWG/FDA guidelines, allele functions, and evidence that supports precision dosing and pharmacogenomics-driven clinical decisions.

Direct Python helpers for KEGG's REST API, covering database metadata, listing, search, retrieval, ID conversion, linkage, and drug interactions to power pathway and gene analysis.

This tool provides access to the Cancer Dependency Map (DepMap) data, derived from genome-wide CRISPR screens, RNAi, and compound sensitivity assays. It allows users to query gene dependency scores, identify cancer-specific vulnerabilities, predict synthetic lethal interactions, and validate potential oncology drug targets across various cancer cell lines.