Skill UI

Analyzes protein sequences to locate canonical N-glycosylation sequons, predict O-glycosylation hotspots, and mutate or design glycosylation sites for therapeutic proteins, vaccines, and biosimilar comparisons using curated glycoengineering resources.

This skill provides comprehensive tools to analyze and engineer protein glycosylation patterns. It scans amino acid sequences for canonical N-glycosylation sequons (N-X-S/T) and predicts O-glycosylation hotspots. Use cases include optimizing therapeutic antibodies, designing vaccine antigens, and characterizing biosimilars by rationally modifying glycan structures for improved stability, function, or immune evasion.