Skill UI

gget is a CLI/Python client that unifies querying over 20+ bioinformatics databases, letting researchers fetch gene info, sequences, BLAST results, structures, and enrichment data interactively or within scripts.

High-performance Rust toolkit with Python bindings for genomic interval analysis, covering overlap detection, coverage track generation, ML tokenization, reference sequence handling, fragment processing, and scoring workflows for sequencing datasets.

Access RCSB PDB to search biomolecular structures via text, sequence, or geometry queries, download coordinate files in PDB/mmCIF/Binary formats, retrieve metadata, and batch-process entries for drug discovery, protein engineering, and structural biology pipelines.

Pysam offers Python bindings to htslib for reading and writing SAM/BAM/CRAM alignments, VCF/BCF variants, and FASTA/FASTQ sequences, enabling coverage stats, pileup analysis, variant queries, and seamless integration into NGS pipelines.

scikit-bio provides a Python-native biological data toolkit for reading/writing FASTA/Newick files, manipulating sequences, building alignments and phylogenies, and calculating diversity metrics for microbiome and ecology workflows.

Direct REST API access to UniProt for searching proteins, fetching FASTA sequences, mapping identifiers, selecting annotations, and streaming large datasets within Python workflows.

Transforms natural-language prompts into Excalidraw JSON diagrams, supporting flowcharts, relationships, mind maps, architecture, DFD, swimlane, class, sequence, and ER views; ideal when users ask to visualize processes or system structures and need editable Excalidraw files.

Analyzes protein sequences to locate canonical N-glycosylation sequons, predict O-glycosylation hotspots, and mutate or design glycosylation sites for therapeutic proteins, vaccines, and biosimilar comparisons using curated glycoengineering resources.

Query the JASPAR REST API and Python helpers to retrieve TF binding profiles, convert PFMs to PWMs, and scan DNA sequences for high-confidence motifs, enabling regulatory variant interpretation, ChIP/ATAC analysis, and TF network construction.

A comprehensive toolkit for reconstructing and analyzing the evolutionary history of biological sequences (genes, proteins, genomes). The standard workflow includes multiple sequence alignment using MAFFT, robust maximum likelihood tree inference with IQ-TREE 2 and FastTree, and advanced visualization/manipulation using ETE3. This skill is essential for studies in viral phylodynamics, microbial genomics, protein family evolution, and molecular clock dating.

This skill assists in crafting effective B2B cold email outreach sequences. It helps write initial emails, build multi-email follow-up sequences, and iterate based on performance data. The focus is on sounding human, personalizing content, and avoiding spam triggers to increase reply rates. Suitable for SDRs, founders, and marketers targeting prospects who haven't opted in.

This expert skill guides you through the entire process of creating, optimizing, and structuring automated email flows, including welcome, nurture, and re-engagement sequences. It ensures every email has a clear purpose, defined metrics, and a structured CTA, allowing you to move users efficiently through the entire customer lifecycle and maximize conversion rates.