Skill UI

A comprehensive, multi-phase quality engineering audit tool designed to test codebases beyond standard unit tests. It first explores the codebase's domain and architecture to derive behavioral requirements, then executes a rigorous sequence including spec-traced functional tests, three-pass code reviews, and a multi-model specification audit (Council of Three). It is specifically engineered to find the critical 35% of real-world defects that structural code review alone might miss. Works with any programming language.

This skill generates a detailed, multi-phase plan for complex, multi-file refactoring projects. It ensures safety by first analyzing the codebase, identifying dependencies, and structuring changes in a safe sequence (e.g., Types first, then implementations, followed by tests and cleanup). It forces the AI to output a comprehensive plan, including rollback steps and verification points, and waits for user confirmation before making any actual code changes.

Automates Salesforce CRM workflows through Rube MCP's Composio toolkit, letting you manage leads, contacts, accounts, opportunities, SOQL queries, and tasks with guided tool sequences and prerequisites.

Automates TikTok content creation via Rube MCP (Composio) by uploading videos/photos, managing published posts, and checking profile stats through the toolkit’s sequence of upload, publish, status polling, and profile APIs.

This technique is used when the required answer in a case query is not directly stated but must be deduced by following a sequence of connected roles, people, or events. It involves mapping complex relationships, such as Victim -> Defendant -> Lawyer -> Witness, to trace indirect connections and reach the final piece of information. Ideal for advanced investigative research and deep knowledge graph traversal.

This skill provides integration with the Adaptyv Bio Foundry API, enabling the automated design, submission, and analysis of protein experiments. Users can submit amino acid sequences for various high-throughput assays, including binding kinetics (BLI/SPR), thermostability, and expression yield. It guides the entire research workflow, from sequence input to final results retrieval, accelerating biopharma discovery.

Biopython is a robust, comprehensive toolkit for computational molecular biology written in Python. It enables users to manipulate biological sequences (DNA, RNA, protein), parse standard formats (FASTA, GenBank, PDB, etc.), and programmatically access major bioinformatics databases like NCBI via Entrez. This skill is ideal for developing complex bioinformatics pipelines, including sequence alignment, structural analysis, and phylogenetic tree construction.

A comprehensive Python package providing a unified interface to over 40 major bioinformatics web services and databases. Use it for complex biological workflows, including cross-database querying (e.g., UniProt, KEGG, ChEMBL), identifier mapping, protein sequence retrieval, pathway analysis, and running sequence similarity searches like BLAST. It streamlines data integration from multiple life science resources into consistent Python code.

DiffDock is a cutting-edge deep learning tool leveraging diffusion models to predict the 3D binding poses of small molecule ligands to protein targets. It supports structure-based drug discovery, enabling single-complex docking, batch virtual screening, and lead optimization. Users can input protein structures (PDB) or sequences, along with diverse ligand formats (SMILES, SDF, MOL2). The tool outputs predicted poses and confidence scores, making it crucial for identifying potential drug candidates, though it does not predict binding affinity.

The ESM skill provides comprehensive tools for computational biology, leveraging ESM3 and ESM-C models. It enables sophisticated protein sequence generation, structure prediction (sequence to 3D structure), inverse folding (structure to sequence design), and generating function-conditioned proteins. Use it for de novo protein design, feature embedding, and advanced structural analysis in bioinformatics workflows.

gget is a comprehensive command-line tool and Python package offering unified access to over 20 genomic databases. It facilitates quick lookups for gene information, sequence analysis (BLAST), protein structures, and expression data, supporting both interactive CLI use and advanced programmatic Python workflows for biological research.

This skill provides comprehensive tools to analyze and engineer protein glycosylation patterns. It scans amino acid sequences for canonical N-glycosylation sequons (N-X-S/T) and predicts O-glycosylation hotspots. Use cases include optimizing therapeutic antibodies, designing vaccine antigens, and characterizing biosimilars by rationally modifying glycan structures for improved stability, function, or immune evasion.